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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PKN2
All Species:
18.48
Human Site:
S590
Identified Species:
31.28
UniProt:
Q16513
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16513
NP_006247.1
984
112035
S590
S
L
G
E
I
D
E
S
S
E
L
R
V
L
D
Chimpanzee
Pan troglodytes
XP_001145367
984
112028
S590
S
L
G
E
I
D
E
S
S
E
L
R
V
L
D
Rhesus Macaque
Macaca mulatta
XP_001110500
1011
111864
T636
L
Y
L
P
Q
E
P
T
F
E
E
T
P
R
T
Dog
Lupus familis
XP_547295
1021
115999
S627
S
L
G
E
I
D
E
S
A
K
L
R
D
L
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8BWW9
983
111611
S589
S
L
G
E
T
D
E
S
S
E
L
R
V
L
D
Rat
Rattus norvegicus
O08874
985
112050
S591
S
L
G
E
I
D
D
S
S
E
L
R
V
L
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506565
993
109767
L618
P
P
R
L
F
L
P
L
E
P
V
A
G
D
S
Chicken
Gallus gallus
XP_422357
1013
114806
E619
E
I
C
E
P
S
S
E
M
K
A
P
D
M
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_700704
970
110327
F590
E
R
G
A
L
T
A
F
A
Y
R
N
D
R
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13678
634
71138
N272
T
T
M
T
S
G
Y
N
S
S
S
C
M
S
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34885
707
80133
N345
S
G
S
S
N
S
E
N
S
G
Y
L
Q
Q
I
Sea Urchin
Strong. purpuratus
XP_787090
799
90414
A437
S
P
L
T
P
P
A
A
R
S
S
P
P
P
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P24583
1151
131500
N760
T
N
P
F
R
D
M
N
S
E
T
F
Q
I
E
Red Bread Mold
Neurospora crassa
P87253
1142
127954
A713
S
R
D
D
E
Y
S
A
Q
Q
Q
Q
G
Y
G
Conservation
Percent
Protein Identity:
100
99.6
46.1
92.8
N.A.
94.6
92.6
N.A.
53.9
87
N.A.
76.4
N.A.
28.3
N.A.
27.6
48.4
Protein Similarity:
100
99.9
63.2
94.7
N.A.
97.2
95.3
N.A.
68.2
91.9
N.A.
85
N.A.
42.3
N.A.
43.7
61.3
P-Site Identity:
100
100
6.6
80
N.A.
93.3
93.3
N.A.
0
6.6
N.A.
6.6
N.A.
6.6
N.A.
20
6.6
P-Site Similarity:
100
100
20
93.3
N.A.
93.3
100
N.A.
6.6
26.6
N.A.
26.6
N.A.
26.6
N.A.
26.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26.1
27.2
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
45.6
45.9
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
46.6
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
15
15
15
0
8
8
0
0
0
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
0
0
8
8
0
43
8
0
0
0
0
0
22
8
36
% D
% Glu:
15
0
0
43
8
8
36
8
8
43
8
0
0
0
8
% E
% Phe:
0
0
0
8
8
0
0
8
8
0
0
8
0
0
0
% F
% Gly:
0
8
43
0
0
8
0
0
0
8
0
0
15
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
29
0
0
0
0
0
0
0
0
8
8
% I
% Lys:
0
0
0
0
0
0
0
0
0
15
0
0
0
0
0
% K
% Leu:
8
36
15
8
8
8
0
8
0
0
36
8
0
36
8
% L
% Met:
0
0
8
0
0
0
8
0
8
0
0
0
8
8
0
% M
% Asn:
0
8
0
0
8
0
0
22
0
0
0
8
0
0
8
% N
% Pro:
8
15
8
8
15
8
15
0
0
8
0
15
15
8
8
% P
% Gln:
0
0
0
0
8
0
0
0
8
8
8
8
15
8
0
% Q
% Arg:
0
15
8
0
8
0
0
0
8
0
8
36
0
15
0
% R
% Ser:
58
0
8
8
8
15
15
36
50
15
15
0
0
8
15
% S
% Thr:
15
8
0
15
8
8
0
8
0
0
8
8
0
0
8
% T
% Val:
0
0
0
0
0
0
0
0
0
0
8
0
29
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
8
8
0
0
8
8
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _